Ralf Kohnen Selected Research

Restless Legs Syndrome (Restless Legs)

1/2016	Post Hoc Analysis of Data from Two Clinical Trials Evaluating the Minimal Clinically Important Change in International Restless Legs Syndrome Sum Score in Patients with Restless Legs Syndrome (Willis-Ekbom Disease).
1/2015	Augmentation of restless leg syndrome (Willis-Ekbom disease) during long-term dopaminergic treatment.
4/2014	What treatment works best for restless legs syndrome? Meta-analyses of dopaminergic and non-dopaminergic medications.
12/2013	Prolonged release oxycodone-naloxone for treatment of severe restless legs syndrome after failure of previous treatment: a double-blind, randomised, placebo-controlled trial with an open-label extension.
12/2013	Relation of the International Restless Legs Syndrome Study Group rating scale with the Clinical Global Impression severity scale, the restless legs syndrome 6-item questionnaire, and the restless legs syndrome-quality of life questionnaire.
6/2012	Augmentation in the treatment of restless legs syndrome with transdermal rotigotine.
3/2012	Efficacy and safety of dopamine agonists in restless legs syndrome.
8/2011	Long-term safety and efficacy of rotigotine transdermal patch for moderate-to-severe idiopathic restless legs syndrome: a 5-year open-label extension study.
6/2011	Ropinirole improves depressive symptoms and restless legs syndrome severity in RLS patients: a multicentre, randomized, placebo-controlled study.
3/2011	Dopamine agonists for restless legs syndrome.

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Ralf Kohnen Research Topics

Disease

24	Restless Legs Syndrome (Restless Legs) 01/2016 - 10/2003
3	Inflammation (Inflammations) 05/2014 - 01/2004
2	Nausea 10/2010 - 12/2008
2	Major Depressive Disorder (Major Depressive Disorders) 01/2010 - 02/2006
1	Glioblastoma (Glioblastoma Multiforme) 10/2016
1	Ileus 12/2013
1	Flank Pain 12/2013
1	Constipation 12/2013
1	Duodenal Ulcer (Curling's Ulcer) 12/2013
1	Vomiting 12/2013
1	Neurobehavioral Manifestations 07/2013
1	Polymyositis 02/2013
1	Dysferlinopathy 02/2013
1	Eyelid Diseases 12/2012
1	Blepharitis 12/2012
1	Calculi (Calculus) 01/2011
1	Urolithiasis 01/2011
1	Depressive Disorder (Melancholia) 01/2011
1	Headache (Headaches) 10/2010
1	Sleepiness 10/2010
1	Hypertension (High Blood Pressure) 05/2009
1	Syncope (Fainting) 12/2008
1	Pain (Aches) 11/2008
1	Complex Regional Pain Syndromes 11/2008
1	Tinnitus 07/2008
1	Ulcerative Colitis 09/2006
1	Colitis 09/2006
1	Crohn Disease (Crohn's Disease) 01/2004
1	Esophageal Neoplasms (Esophageal Cancer) 08/2003
1	Neoplasms (Cancer) 08/2003
1	Ulcer 08/2003
1	Schizophrenia (Dementia Praecox) 05/2003

Drug/Important Bio-Agent (IBA)

11	Dopamine Agonists (Dopamine Agonist)IBA 01/2015 - 12/2004
10	rotigotine FDA Link 01/2016 - 12/2004
6	Levodopa (L Dopa)FDA LinkGeneric 01/2011 - 10/2003
3	Pharmaceutical PreparationsIBA 12/2012 - 12/2008
3	Antidepressive Agents (Antidepressants)IBA 06/2011 - 02/2006
2	Ointments (Pastes)IBA 05/2014 - 12/2012
2	Cabergoline FDA LinkGeneric 04/2007 - 06/2004
2	Biomarkers (Surrogate Marker)IBA 09/2006 - 01/2004
1	MethyltransferasesIBA 10/2016
1	Temozolomide (Temodar)FDA LinkGeneric 10/2016
1	Bevacizumab (Avastin)FDA Link 10/2016
1	O(6)-Methylguanine-DNA MethyltransferaseIBA 10/2016
1	Irinotecan (Camptosar)FDA LinkGeneric 10/2016
1	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2014
1	hydrocortisone acetate (Cortifoam)FDA LinkGeneric 05/2014
1	Naloxone (Narcan)FDA LinkGeneric 12/2013
1	Opioid Analgesics (Opioids)IBA 12/2013
1	Oxycodone (Oxycontin)FDA LinkGeneric 12/2013
1	Calcium Channels (Calcium Channel)IBA 07/2013
1	LigandsIBA 07/2013
1	deflazacortIBA 02/2013
1	SteroidsIBA 02/2013
1	Local Anti-Infective Agents (Antiseptics)IBA 12/2012
1	bibrocatholIBA 12/2012
1	ropinirole (Requip)FDA LinkGeneric 06/2011
1	Dopamine (Intropin)FDA LinkGeneric 01/2011
1	Carboxy-LyasesIBA 01/2011
1	Parasympatholytics (Antispasmodics)IBA 01/2011
1	Analgesics (Analgesic Drugs)IBA 01/2011
1	Terpenes (Terpenoids)IBA 01/2011
1	Sertraline (Zoloft)FDA LinkGeneric 01/2011
1	SDMIBA 05/2009
1	EnzymesIBA 07/2008
1	Ferritins (Ferritin)IBA 07/2008
1	levodopa drug combination benserazideIBA 04/2007
1	TabletsIBA 02/2006
1	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 02/2006
1	Mirtazapine (Rexer)FDA LinkGeneric 02/2006
1	Orosomucoid (Seromucoid)IBA 01/2004
1	C-Reactive ProteinIBA 01/2004
1	BenserazideIBA 10/2003
1	Antipsychotic Agents (Antipsychotics)IBA 05/2003

Therapy/Procedure

7	Therapeutics 01/2015 - 08/2003
4	Transdermal Patch 08/2011 - 12/2008
2	Moxibustion 09/2006 - 01/2004
2	Aftercare (After-Treatment) 09/2006 - 01/2004
1	Lithotripsy (Extracorporeal Shockwave Lithotripsy) 01/2011
1	Occlusal Splints 11/2008
1	Ligation 08/2003
1	Drug Therapy (Chemotherapy) 05/2003